Liver iron concentration, stainable iron, and total body storage iron
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چکیده
منابع مشابه
Liver iron concentration, stainable iron, and total body storage iron.
Liver iron concentration has been determined chemically in 154 liver biopsies and the findings compared with the routine histological assessment of stainable parenchymal iron, performed by an independent observer. There was a significant correlation between liver iron concentration and histochemical grading but the relationship did not have a normal linear form. Absence of stainable iron corres...
متن کاملImmunoradiometric serum ferritin concentration compared with stainable bone-marrow iron as indices to iron stores.
Immunoradiometric analysis has made it possible to measure ferritin reliably in serum. The determination is a sensitive means of assessing body iron because concentrations of ferritin closely parallel the body's reticuloendothelial iron stores. The information provided is similar to that obtained from bone-marrow aspirates or biopsies stained for iron with Prussian Blue. Comparative studies ind...
متن کاملRelationship of hepatic iron concentration to histochemical grading and to total chelatable body iron in conditions associated with iron overload.
A simple method based on atomic absorption spectrophotometry and using protein concentration as the reference standard was used for measuring the total tissue iron concentration in needle liver biopsy specimens from 47 patients with varying levels of body iron stores. The values obtained showed a close correlation over a wide range with measurements of total chelatable body iron stores. A compa...
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We recently reported that parenteral iron therapy is associated with a characteristic pattern of iron staining on bone marrow aspirate smears. We now present clinical information from 6 patients who received parenteral iron and, at one or more points in follow-up, were found to have low or borderline low serum ferritin levels and/or serum iron levels, even though marrow aspirate smears revealed...
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in borderline cases. The routine use of other biomar-ker assays, such as HFABP in conjunction with tGST activity, could provide complementary information on the potential allograft " viability ". This is illustrated by the fact that there was better segregation of donor categories (controlled vs uncontrolled) with HFABP than with tGST activity. This finding therefore warrants continued evaluati...
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ژورنال
عنوان ژورنال: Gut
سال: 1974
ISSN: 0017-5749
DOI: 10.1136/gut.15.5.411